Dimethyl Sulfoxide
Sigma Aldrich Phenyl vinyl sulfoxide
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Sigma Aldrich Fine Chemicals Biosciences DIMETHYL SULFOXIDE 5X5ML
NC3592569 DIMETHYL SULFOXIDE 5X5ML
PROTIDE PHARMACEUTICAL STEMSOL 99.9% DMSO USP VIAL GLASS 50ML
STEMSOL 99.9% DMSO USP VIAL GLASS 50ML
VWR INTERNATIONAL LLC Dimethyl sulfoxide | MW: 78.14 g/mol | 67-68-5 | MFCD00002089 | 5 x 10mL
Dimethyl sulfoxide | Purity: ≥99.9% | Ultra Pure Grade | MW: 78.14 g/mol | 67-68-5 | MFCD00002089 | 5 x 10mL
Apexbio Technology LLC Trametinib DMSO solvate 1187431-43-1 10mM (in 1mL DMSO)
Trametinib DMSO solvate (CAS 1187431-43-1) is a potent allosteric inhibitor of MEK1 and MEK2 that acts through an ATP-noncompetitive mechanism In preclinical models it has demonstrated broad antitumor activity notably in colorectal cancer cell lines such as HT-29 and COLO205 Trametinib induces the expression of p15 and p27 suppresses cyclin D1 promotes RB dephosphorylation and G1 cell cycle arrest and reduces thymidylate synthase expression Furthermore it inhibits ERK1/2 phosphorylation leading to growth suppression in B-RAF mutant tumor cells Trametinib serves as a valuable tool for studying MAPK pathway signaling and targeted cancer therapeutics
Sigma Aldrich Fine Chemicals Biosciences Dimethyl sulfoxide | 67-68-5 | MFCD00002089 |
Dimethyl sulfoxide | 67-68-5 | MFCD00002089 |